2-Chlorophenylboronic Acid CAS 3900-89-8: Uses, Specifications, and Sourcing Guide

2-Chlorophenylboronic acid, also called 2-chlorobenzeneboronic acid, is an arylboronic acid used as a building block in organic synthesis. Its CAS number is 3900-89-8, and its molecular formula is C₆H₆BClO₂, with a molecular weight of approximately 156.38 g/mol. Buyers most often evaluate it for carbon–carbon coupling work, especially Suzuki–Miyaura reactions, and should confirm the required purity, documentation, quantity, and delivery terms before ordering.

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Key Takeaways

• 2-Chlorophenylboronic acid is an ortho-chlorinated arylboronic acid supplied for use as a synthetic intermediate.
• Its boronic acid group supports cross-coupling chemistry, while the chlorine substituent can provide an additional point for further chemical transformation.
• Product specifications, including assay, impurity profile, packaging, and storage guidance, should be confirmed against the supplier’s current documentation.
• For a reliable purchasing comparison, provide the intended application, target quantity, required specification, and destination market when requesting a quotation.

Who This Guide Is For

This guide is intended for procurement teams, process chemists, research groups, and chemical distributors assessing 2-Chlorophenylboronic acid CAS 3900-89-8. It explains the compound’s general role, the information to review in a product specification, and the practical questions to ask suppliers. It is not a substitute for a project-specific reaction assessment or the supplier’s safety documentation.

Buyers at different stages may need different levels of information. A laboratory-scale purchaser may prioritize identity, assay, and a manageable pack size, while a process-development or production team may also need batch consistency, supply planning, and shipment documentation. Sharing the intended use early helps a supplier respond with relevant information rather than a generic product description.

Basic Concept and Chemical Context

Structure and identity

The molecule contains a benzene ring bearing a boronic acid group and a chlorine substituent at the adjacent, or 2-position. This arrangement makes it an ortho-substituted arylboronic acid. When comparing suppliers, use both the chemical name and CAS number to reduce the risk of confusing it with another chlorophenylboronic acid positional isomer.

The boronic acid functionality is the principal feature used in many coupling reactions. The chlorine atom is part of the aromatic structure and may be retained in a product or considered for subsequent transformations, depending on the reaction design. Whether either functional group performs as intended depends on the substrate, catalyst system, solvent, and reaction conditions; the compound alone does not guarantee a particular outcome.

Common synthetic role

A common use is as an aryl coupling partner in Suzuki–Miyaura carbon–carbon bond formation. In broad terms, the reaction can connect the aryl group from the boronic acid to a suitable coupling partner under an appropriate catalytic system. Applications may include the preparation of substituted biaryl intermediates and other aromatic compounds used in research or chemical development.

The compound may also be considered in routes where the chlorine substituent is useful as a retained substituent or as a handle for later chemistry. Route selection should account for functional-group compatibility and the reactivity of both the boronic acid and the aryl chloride. Buyers should avoid assuming that a literature procedure transfers directly to a different substrate, scale, or process environment.

Specifications and Material Options

There is no single specification that is automatically appropriate for every project. The required grade depends on the intended reaction, downstream impurity controls, development stage, and purchasing requirements. Ask the supplier for the current specification and batch-specific Certificate of Analysis (CoA), and compare the reported methods and limits rather than relying on a product name alone.

As a purchasing example, a buyer might request material meeting an assay target of at least 98%; this is an example of a buyer-defined requirement, not a claim about every available batch or Maison Chemical’s standard specification. The supplier should confirm whether the requested limit is available and how it is tested before the buyer places an order. Where analytical method details matter, ask for the method or relevant documentation during the qualification process.

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Matching the Material to the Application

For exploratory synthesis, a buyer may begin by checking identity and a suitable assay level, then evaluate the material in the intended reaction. For process development, review the specification alongside route robustness, impurity fate, and the material’s handling requirements. For recurring procurement, ask how the supplier manages specification changes and communicates batch documentation.

Do not select material solely by the highest stated purity. A higher assay may be valuable when the reaction or downstream control strategy requires it, but the decision should also consider test method, impurity types, batch availability, and total project cost. If the compound will be used in a sensitive route, the process team should define the critical quality attributes before requesting quotations.

Buyer Selection Framework

Define the technical requirement

Start with the identity, intended use, and minimum acceptable specification. State whether the material is for research, process development, or another defined purpose, and identify any known impurity or documentation requirements. If the chemistry is still under evaluation, distinguish confirmed requirements from preferences so suppliers can propose an appropriate option.

Compare commercial terms

Request quotations for the quantities relevant to your project, such as a laboratory quantity in grams or a production-planning quantity in kilograms. These units describe possible inquiry quantities, not a promise of standard pack sizes or stock availability. Compare the quoted price with the specification, packaging, lead time, shipping terms, and any documentation included.

MOQ and lead time can vary with quantity, production planning, packaging, and destination. Ask whether the quoted lead time refers to dispatch or delivery, and whether it depends on confirmation of the order or other conditions. If timing is critical, request an explicit written estimate rather than inferring availability from a product listing.

Evaluate the supplier

A useful supplier review covers product identity, specification transparency, batch documentation, communication, and the ability to discuss project requirements. Ask for a current CoA example where available, and confirm that the document corresponds to the offered grade and batch when purchasing. Also verify that packaging and shipment arrangements are appropriate for your destination and internal receiving procedures.

Maison Chemical supplies chemicals for B2B buyers and can discuss inquiries for 2-Chlorophenylboronic acid CAS 3900-89-8. To support an accurate response, include your target quantity, required assay or other specification, intended application, destination, and preferred delivery schedule. Product availability, MOQ, lead time, and documentation should be confirmed for the specific inquiry.

Common Sourcing Mistakes to Avoid

• Relying on the name alone: Include CAS 3900-89-8 and confirm the 2-substitution pattern to distinguish the material from positional isomers.
• Comparing assay figures without context: Check the test method and reporting basis, not only the numerical limit.
• Assuming stock or lead time: Obtain a current quotation and confirm whether the estimate covers dispatch or delivery.
• Leaving documentation needs until after ordering: Identify CoA, safety, labeling, or other required documents during supplier evaluation.
• Overlooking route-specific requirements: Have the technical team assess compatibility and impurity controls for the intended chemistry.

Conclusion and Next Steps

2-Chlorophenylboronic acid CAS 3900-89-8 is an ortho-chlorinated arylboronic acid commonly considered as a building block for coupling chemistry and aromatic intermediate synthesis. Its molecular weight is approximately 156.38 g/mol, but the correct purchasing choice depends on the required specification, application, documentation, and supply conditions. The most dependable approach is to confirm identity and batch requirements first, then compare quotations on equivalent commercial terms.

For a sourcing inquiry, send Maison Chemical your target quantity, specification, destination, and requested delivery timing. Include any application-specific documentation or impurity requirements so we can assess the inquiry against the appropriate product and supply details. Confirm all final specifications and commercial terms before placing an order.

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