10 Essential Questions to Ask When Considering 1,4-Butanediol (BDO) Purchase

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Wuhanwingroup

7 min read

Aug 20,

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1. What is 1,4-Butanediol (BDO) | CAS 110-63-4?

1,4-Butanediol (BDO) is a clear, non-corrosive liquid that boasts a high boiling point and a low toxicity level.

This compound is fully soluble in water along with various alcohols, ketones, esters, and glycol ethers, although it may show limited solubility in common hydrocarbons such as aliphatic and aromatic compounds.

Manufactured by Lyondell Chemical Company using a proprietary multi-step process involving propylene oxide as a base, this chemical is crucial due to its hydrophobic properties and terminal hydroxyl groups, making it an important intermediate in producing numerous commercial products.

2. How Does 1,4-Butanediol (BDO) Operate in the Body?

Upon ingestion, BDO converts to gamma hydroxybutyrate (GHB), a substance that depresses brain activity, potentially leading to loss of consciousness and impaired respiration.

Neurotoxicity Concerns

Research indicates that GHB can negatively affect cognitive function by impairing various types of memory in rats, related to a reduction in NMDA receptor expression.

Tolerance and Addiction

1,4-Butanediol is recognized for its potential for physical and psychological addiction. Discontinuation after regular use can lead to withdrawal symptoms similar to those seen with other depressants like alcohol and benzodiazepines.

3. Common Applications of 1,4-Butanediol

1,4-Butanediol serves as a key raw material across several industries including pharmaceuticals, textiles, paper production, automotive, and personal care products.

Polymer Manufacturing

BDO is instrumental in the creation of polybutylene terephthalate (PBT), a thermoplastic known for its strength, thermal stability, and wide-ranging applications including automotive and electrical components.

Polyester Production

This compound is also vital in the production of polyurethanes and polyesters, enhancing their mechanical properties across various temperature ranges.

4. What Are the Benefits of Using 1,4-Butanediol?

Notably, BDO acts as a skin moisturizer, penetrating deeply and replenishing water levels in the skin, making it a valuable ingredient in skincare products.

5. Possible Side Effects of 1,4-Butanediol

High doses can lead to adverse reactions such as nausea, dizziness, and sedation. Excessive consumption may even result in severe outcomes, including death.

6. Proper Handling and Storage of 1,4-Butanediol

It's essential to store BDO appropriately as it can solidify below 19°C, and specific precautions should be taken in the presence of strong acids.

7. Legal Status of 1,4-Butanediol

In the United States, BDO is not federally scheduled but is regulated in certain states. The legal landscape varies significantly internationally.

8. Where Can You Purchase 1,4-Butanediol?

Online purchases can be made from various manufacturers. It is crucial to verify their legitimacy based on state regulations prior to making a purchase.

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9. Packaging Options for 1,4-Butanediol

This compound is typically supplied in factory-sealed drums and bulk heated ISO tanks for large-scale applications.

10. What is the Shelf Life of 1,4-Butanediol?

When stored properly at ~20°C, unopened BDO has a shelf life of 2 years, although once opened, it absorbs moisture from the air.

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